Frequency Specific Microcurrent for Treatment of Knee Osteoarthritis: A Case Report by Muizz Mushtaque Shaikh

Published: 2025

Knee osteoarthritis (OA) is a chronic degenerative joint disorder marked by cartilage destruction, inflammation, and functional disability. Conventional physiotherapy and analgesics often provide only temporary relief, while surgical options like total knee replacement are invasive and costly. Frequency Specific Microcurrent (FSM) therapy, which uses low-amperage currents paired with condition-specific frequencies, has shown potential in pain modulation and tissue healing but remains underexplored for knee OA.

SCLERODERMA – Frequency Specific Microcurrent Improves Hand Function and Raynaud's Symptoms in Scleroderma: Results of Two Pilot Studies

Published: 2025

The degree of improvement in hand function obtained over a very short treatment period of 45 minutes to 1 hour was significant.

Frequency Specific Microcurrent in the Treatment of Dense Breast Tissue: A Case Report

Published: 2024

This case report follows the use of Frequency Specific Microcurrent (FSM) to treat a 54-year-old woman with dense breast tissue. Mammograms which were performed in 2018 and 2021 showed heterogeneously dense breast tissue, category C. The 2021 mammogram procedure was excruciatingly painful for the patient during the breast compression. FSM therapy was used to address the dense tissue and associated pain.

Effect of Adjuvant Frequency Specific Microcurrents on Pain and Disability in Patients Treated with Physical Rehabilitation for Neck and Low Back Pain

Published: 2024

To evaluate the efficacy of adjuvant Frequency Specific Microcurrent (FSM) application on pain and disability in patients treated with physical rehabilitation for mechanical low back pain (LBP) and neck pain (NP).

A Pulsed DC Electric Field Affects P2-Purinergic Receptor Functions by Altering the ATP Levels in Vitro and in Vivo Systems

Published: 2002

Recently it was shown that extracellular ATP, acting through purinergic receptors, has many physiological functions, including opening of Ca2+ -ion channels, activation and mediation of signal transduction mechanisms as well as activation of the pain sensation. Since electrical stimulation is also known to affect many signal transduction processes, this study explores the relationship between electric fields and ATP levels.

Activation of Signal-Transduction Mechanisms May Underlie the Therapeutic Effects of an Applied Electric Field

Published: 2001

There are numerous reports of positive clinical effects after exposure to applied electric fields of relatively small strength (in the 103 to 104 V m–1 range) which are variable with low to medium frequency (below 150 Hz). Effects reported include the alleviation of pain, decreased inflammation, wound and bone fracture healing, and enhanced tissue regeneration.

Impedance-Controlled Microcurrent Therapy for Managing Radiation-Induced Fibrosis in Head and Neck Cancer Patients

Published: 1999

To evaluate the effectiveness of impedance-controlled microcurrent therapy for managing treatment sequelae in head-and-neck cancer patients. Methods and Materials: Between January 1998 and June 1999, 26 patients who were experiencing late effects of radiotherapy were treated b.i.d. with impedance-controlled microcurrent therapy for 1 week.

Cytokine Changes with Microcurrent Treatment of Fibromyalgia

Patients who have fibromyalgia syndrome (FMS) associated with cervical spine trauma have distinct pain descriptors and physical examination findings. Currently, there is no effective treatment for fibromyalgia. Microamperage current provides physiologic current flow and has been used in the treatment of some pain syndromes. In this uncontrolled retrospective analysis of cytokine changes, microcurrent treatment showed significant improvements.

Effects of Aerobic Exercise Associated with Abdominal Microcurrent

To analyze the short- and long-term effects of microcurrent used with aerobic exercise on abdominal fat (visceral and subcutaneous). Forty-two female students from a university population were randomly assigned into five groups: intervention group (IG) 1 (n=9), IG2 (n=9), IG3 (n=7), IG4 (n=8), and placebo group (PG) (n=9).

Fibromyalgia, Chronic Fatigue, and Multiple Chemical Sensitivities – A Unified Hypothesis

When they arrive in your office, they all look the same with minor variations, rather like identical suburban tract houses with different floor plans and exterior colors. They have body pain that varies between a 4-5/10 and a 6-8/10. They don't sleep.

Frequency Specific Microcurrent for Treatment of Longstanding Congenital Muscular Torticollis

This case describes the first episode of care, using conservative treatment, massage, and frequency-specific microcurrent (FSM), for a 19-month-old boy with grade 8 left congenital muscular torticollis with fibrotic nodules. Methods: Ten weeks of physical therapy provided stretching, strengthening, massage, and parent education, adding FSM in weeks 3 to 10 to address the fibrotic tissue.

Frequency Specific Microcurrent Resolves Chronic Pain and Adhesions After Ulnar Transposition Surgery

Frequency specific microcurrent (FSM) has been used to treat myofascial pain syndrome [1,2] fibromyalgia associated with spine trauma [3], delayed onset muscle soreness [4], acute and chronic neuropathic pain [5] and chronic scarring in burn patients [6]. In this case, its use was modified to address chronic pain and adhesions following ulnar transposition surgery.

Frequency-Specific Microcurrent as Adjunctive Therapy for Three Wounded Warriors

Frequency specific microcurrent (FSM) has been used to treat myofascial pain syndrome [1,2] fibromyalgia associated with spine trauma [3], delayed onset muscle soreness [4], acute and chronic neuropathic pain [5] and chronic scarring in burn patients [6]. In this case, its use was modified to include not only pain management but also addressing the complex needs of wounded warriors.

Mental Health, the Brain, and PTSD

To evaluate the effectiveness of impedance-controlled microcurrent therapy for managing treatment sequelae in head-and-neck cancer patients. Methods and Materials: Between January 1998 and June 1999, 26 patients who were experiencing late effects of radiotherapy were treated b.i.d. with impedance-controlled microcurrent therapy for 1 week.

Microcurrent Experimental Results

Test hypothesis using an ear inflammation model – Arachadonic acid induced swelling. Male SKh-1 albino hairless mice aged 6 weeks. Ears were measured with a micrometer, 5μl of 25mg/ml of Arachadonic acid in ethanol, was painted on both sides of the ear and both ears were treated. FSM was applied to test the anti-inflammatory effects of frequency-specific microcurrent.

Microcurrent Treatment of Low Back Pain | Chronic Low Back Myofascial Pain | Lumbar Pain

Chronic low back pain associated with myofascial trigger point activity has been historically refractory to conventional treatment (Pain Research and Management 7 (2002) 81). In this case series study, an analysis of 22 patients with chronic low back pain, of 8.8 years average duration, is presented. Following treatment with frequency-specific microcurrent, significant improvements were observed.

NON-PHARMACOLOGIC TREATMENT OF SHINGLES – Treatment with Frequency Specific Microcurrent

In unpublished anecdotal reports of Frequency Specific Microcurrent (FSM) treatments during the last twelve years, one frequency combination has been observed consistently to eliminate the pain and shorten the course of shingles. That frequency combination— 230 Hz on one channel and 430 Hz on the second channel—applied simultaneously using 150 microamps has shown remarkable results.

Nonpharmacologic Treatment of Neuropathic Pain Using Frequency Specific Microcurrent

Frequency-specific microcurrent (FSM) has been used for 10 years by numerous practitioners in various specialties (MDs, DCs, NDs, PTs) to treat myofascial pain and neuropathic pain in clinical practice (1-3). This retrospective analysis of patients treated for neuropathic pain in the author's clinic presents a collected case report in patients with various neuropathic pain conditions.

Significant Enhancement of ATP Synthesis in Cardiomyocytes By Electric Microcurrent

The cardiomyocytes of failing hearts show a significant reduced ability to synthesize ATP. On the one hand, the ATP synthesis depends on the level of the H+ based mitochondrial membrane potential which is impaired in heart failure and which in turn correlates to the electron transfer rate of the respiratory chain. This study demonstrates that electric microcurrent can significantly enhance ATP synthesis in cardiomyocytes.

The Effects of Electric Currents on ATP Generation, Protein Synthesis, and Membrane Transport in Rat Skin

The skin of locally inbred, male Wistar R rats, just finishing their first hair-cycle at 21 days of age, was used. In these circumstances, metabolism of the skins was in rest phase. After removing the hair of the back by plucking and disinfection with 0.05% chlorhexidine (ICI), the skin samples were prepared for analysis of ATP generation, protein synthesis, and membrane transport.

The Efficacy of Frequency Specific Microcurrent Therapy on Delayed Onset Muscle Soreness

This study compared the effects of frequency specific microcurrent (FSM) therapy versus sham therapy in delayed onset muscle soreness (DOMS) in order to determine whether specific frequencies on two channels would produce better results than single channel single frequency microcurrent therapy which has been shown to be ineffective as compared to placebo.

The Use of Micro Current and Autocatalytic Silver Plated Nylon Dressings in Human Burn Patients

The use of autocatalytic silver plated nylon dressings (Silverlon®) as an antimicrobial agent in wound management is well documented in both animal and human studies. Also, the use of micro current in the treatment of wound healing in association with Silverlon has been shown to enhance silver release, improve anti-microbial activity, and accelerate wound healing.

Visceral and Somatic Disorders: Tissue Softening with Frequency Specific Microcurrent

Frequency-specific microcurrent (FSM) is an emerging technique for treating many health conditions. Pairs of frequencies of microampere-level electrical stimulation are applied to particular places on the skin of a patient via combinations of conductive graphite gloves, moistened towels, or gel electrode patches. A consistent finding is a profound and palpable tissue softening effect.