Knee osteoarthritis (OA) is a chronic degenerative joint disorder marked by cartilage destruction, inflammation, and functional disability. Conventional physiotherapy and analgesics often provide only temporary relief, while surgical options like total knee replacement are invasive and costly. Frequency Specific Microcurrent (FSM) therapy, which uses low-amperage currents paired with condition-specific frequencies, has shown potential in pain modulation and tissue healing but remains underexplored for knee OA.